2022 Mercedes-Benz E-Class Review, Pricing, and Specs


There are sportier alternatives to the 2022 Mercedes-Benz E-class, but few are as seamlessly high-class and high-tech. While the behind-the-wheel experience isn’t as exciting as that of its AMG-tuned twin­–the separately reviewed 429-hp E53–the regular E is subdued and serene. Its cabin is beautifully appointed, remarkably quiet, and fitted with flashy tech features such as the dual displays embedded in its dashboard. The E350 sedan is powered by an common-for-the-segment turbo four, but the E450 enjoys a sweet turbocharged straight-six. This strong, smooth mill is available in the sedan and standard on the coupe and cabriolet. Regardless of the powerplant, all body styles supplement their classy interiors with a cushy and composed ride. Add the 2022 E-class’s roster of advanced driver assists to its luxury appointments and quality assembly, and its esteemed position among mid-size luxury cars is evident.

What’s New for 2022?

For 2022, Mercedes improves the E-class lineup with minor alterations. Every model now comes standard with automatic high-beam headlights. Also, several new paint colors are available. The expanded list includes Nautical Blue metallic, Starling Blue metallic, Manufacktur Moonlight White, and Manufacktur Starling Blue metallic.

Pricing and Which One to Buy

    We recommend the sedan body style and advocate for the E450, with its potent six-cylinder powertrain and standard 4Matic all-wheel-drive system. It comes standard with blind-spot monitoring, a fully digital dashboard, heated front seats with memory settings, an infotainment system with Apple CarPlay and Android Auto, and passive entry. To that we’d add the optional air suspension, head-up display, heated steering wheel, multi-contour front seats with massage functions, and ventilated front-seat cushions.

    Engine, Transmission, and Performance

    Every E-class features an obedient nine-speed automatic transmission that pairs with three distinct engines. The E350 has a turbocharged four-cylinder that makes 255 horsepower and 273 pound-feet of torque. It pairs with either rear- or all-wheel drive. The E450 is powered by a turbocharged inline-six-cylinder engine with a 48-volt hybrid system that doubles as an electric supercharger. The setup sends 362 horsepower and 369 pound-feet to all four wheels. Since the E-class is a comfort-biased car, its handling is competent but not sporty. It leans in corners, but it rarely feels overwhelmed when pushed hard. With the optional air suspension in its Comfort setting, the ride is creamy, and the E-class is perfect for gobbling up lots of road. It glides over pavement imperfections with only slight notification of such unpleasantries communicated to the cabin. With the drive-mode selector set to either Comfort or Eco, the steering is nicely weighted—not too light, not too heavy—and feels accurate. The E-class tracks straight on the freeway with a solid and predictable nature, and feedback from the road is muted. Unfortunately, the E450 we tested needed a long 187 feet to stop from 70 mph.

    Fuel Economy and Real-World MPG

    The four-cylinder E350 earned ratings of 22 mpg city and 31 mpg highway with rear-wheel drive and 22 mpg city and 30 mpg highway with all-wheel drive. The more powerful E450 model is just as efficient with ratings of 23 mpg city and 30 mpg highway. Once we have the chance to test the different powertrains on our 75-mph highway fuel economy test route, we can evaluate their real-world mpg. For more information about the E-class’s fuel economy, visit the EPA’s website.

    Interior, Comfort, and Cargo

    The E-class’s cabin is beautifully detailed with brushed aluminum, lovely wood, and some of the most comfortable seats we’ve ever tested. Every model comes standard with customizable ambient interior lighting, heated front seats, a 12.3-inch digital gauge cluster, and memory settings for the driver’s and front passenger seat. Desirable options include a head-up display, massaging front seats, a panoramic sunroof, and ventilated front-seat cushions. Under its shapely rear end is a trunk that offers less space than some rivals, but the Benz has them beat when it comes to interior cubby storage. Lowering the rear seatbacks opens up much more space for hauling cargo, but they don’t fold completely flat so loading heavy items may feel like a chore. We still managed to fit 18 of our carry-on suitcases inside the sedan with the rear seats stowed. Both the coupe and convertible models offer a 10-cubic-foot trunk; with the top down, though, the cabriolet model’s available space shrinks considerably. We could only fit two carry-on suitcases inside the trunk with the convertible’s top stowed, but the coupe managed to hold five.

    Infotainment and Connectivity

    The E-class comes standard with a 12.3-inch touchscreen infotainment system, which can be controlled in myriad ways that include a touchpad on the center console as well as voice-activated commands. Despite the litany of controls, the interface isn’t as intuitive to operate as its predecessor was, which featured a useful rotary controller on the center console. The MBUX system comes standard with Apple CarPlay and Android Auto. Those who want fancier features can upgrade to a powerful Burmester stereo and wireless charging.

    Safety and Driver-Assistance Features

    Although it comes standard with several driver assists, such as automated emergency braking and blind-spot monitoring, most other equipment costs extra. For more information about the E-class’s crash-test results, visit the National Highway Traffic Safety Administration (NHTSA) and Insurance Institute for Highway Safety (IIHS) websites. Key safety features include:

    • Available adaptive cruise control with stop-and-go technology
    • Available lane-departure warning and lane-keeping assist
    • Available automatic high-beam headlights

      Warranty and Maintenance Coverage

      Mercedes-Benz covers the E-class lineup with a competitive limited and powertrain warranty. However, unlike rivals such as BMW and Jaguar, the company doesn’t provide any amount of complimentary maintenance.

      • Limited warranty covers four years or 50,000 miles
      • Powertrain warranty covers four years or 50,000 miles
      • No complimentary scheduled maintenance



        2021 Mercedes-Benz E450 4Matic


        front-engine, all-wheel-drive, 5-passenger, 4-door wagon

        BASE PRICE (C/D EST)


        turbocharged and intercooled DOHC 24-valve inline-6, aluminum block and head, direct fuel injection

        182 in3, 2991 cm3

        362 hp @ 6100 rpm

        369 lb-ft @ 1600 rpm


        9-speed automatic


        Wheelbase: 115.7 in

        Length: 194.3 in

        Width: 72.9 in

        Height: 57.8 in

        Curb weight: 4500 lb


        60 mph: 4.7 sec

        100 mph: 11.8 sec

        1/4 mile: 13.3 sec

        Top speed: 130 mph


        Combined/city/highway: 23/20/28 mpg

        More Features and Specs

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